Application Method

Summary

7900 Application Method for Elemental Impurities in Pharma, using China Pharmacopoeia.

Compatible Sample Types

Simple aqueous matrices and acid digested samples up to 0.4% dissolved solids.

Pre-Defined Analytes

Cu, As, Cd, Hg, Pb

Comment

Method uses General Purpose plasma conditions and He mode only. The selection of an appropriate internal standard should consider the analyte and the sample matrix.

Required Hardware

7900, x-Lens, Micro Mist Nebulizer

Summary

7900 Application Method for Elemental Impurities in Pharma, using USP<232>/ICH Q3D

Compatible Sample Types

Simple aqueous matrices and acid digested samples up to 0.4% dissolved solids

Pre-Defined Analytes

Li, V, Cr, Co, Ni, Cu, As, Se, Mo, Ru, Rh, Pd, Ag, Cd, Sn, Sb, Ba, Os, Ir, Pt, Au, Hg, Tl, Pb

Comment

Method uses General Purpose plasma conditions and He mode only, but requires the 7900. User Access Control option software is required for regulated pharma analysis. The selection of an appropriate internal standard should consider the analyte and the sample matrix.

Required Hardware

7900, x-Lens, Micro Mist Nebulizer

Summary

7900 Application Method for EPA200.8 (No minerals, without ORSs)

Compatible Sample Types

Application Method for low matrix aqueous or acidic samples (up to 0.1% Total Dissolved Solids), including drinking water, tap water, industrial water, riverine water, lake water, pond water and surface water except seawater. Also suitable for closed-vessel acid digested or extracted samples, after dilution to <0.1% Total Dissolved Solids.

Pre-Defined Analytes

Li, Be, Al, V, Cr, Mn, Co, Ni, Cu, Zn, As, Se, Mo, Ru, Rh, Pd, Cd, Ag, Sn, Sb, Ba, Ho, Hg, Tl, Pb, Th, U

Comment

Uses Low Matrix plasma conditions, and no gas mode only.

Required Hardware

7900, x-Lens, Micro Mist Nebulizer

Summary

7900 Application Method for EPA6020

Compatible Sample Types

Application Method for low or medium matrix samples (up to 0.3% Total Dissolved Solids), including diluted seawater, groundwater and mineral water, acid digested or extracted soil, sediment, sludge and industrial waste samples.

Pre-Defined Analytes

Li, Be, Na, Mg, Al, K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Rh, Ag, Cd, Sn, Sb, Ba, Ho, Hg, Tl, Pb

Comment

Method is suitable only for the 7900, due to the short pre-defined cell gas stabilization time. Uses General Purpose plasma conditions, and no gas, and He cell modes.

Required Hardware

7900, x-Lens, Micro Mist Nebulizer

Summary

7900 Application Method for Drinking Water (with ORS)

Compatible Sample Types

Application Method for low matrix aqueous or acidic samples (up to 0.1% Total Dissolved Solids), including drinking water, tap water, industrial water, except seawater. Also suitable for closed-vessel acid digested or extracted samples, after dilution to <0.1% Total Dissolved Solids.

Pre-Defined Analytes

Na, Mg, Al, K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Sr, Mo, Rh, Ag, Cd, Sn, Ba, Hg, Tl, Pb, Th, U

Comment

Method is suitable only for the 7900, due to the short pre-defined cell gas stabilization time. Uses Low Matrix plasma conditions, and no gas, and He cell modes

Required Hardware

7900, x-Lens, Micro Mist Nebulizer

Summary

7900 Application Method for Ultra-Pure Water

Compatible Sample Types

Ultra-Pure Water

Pre-Defined Analytes

Li, Be, B, Na, Mg, Al, Si, P, S, K, Ca, Sc, Ti, V, Cr, Mn, Fe, Ni, Co, Cu, Zn, Ga, Ge, As, Se, Br, Rb, Sr, Y, Zr, Nb, Mo, Ru, Rh, Pd, Ag, Cd, In, Sn, Sb, Te, I, Cs, Ba, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Hf, W, Ta, Re, Os, Ir, Pt, Au, Hg, Tl, Pb, Bi, Th, U

Comment

Method is suitable only for the 7900, due to the use of cool plasma conditions for some analytes.

Required Hardware

7900, s-Lens, 2.5mm injector torch, quartz spray chamber (G3280-80008), quartz connector tube (straight), MicroFlow Nebulizer, Pt sampling cone, Pt skimmer cone, Brass skimmer base

Summary

7800 Application Method for Elemental Impurities in Pharma, using China Pharmacopoeia.

Compatible Sample Types

Simple aqueous matrices and acid digested samples up to 0.4% dissolved solids.

Pre-Defined Analytes

Cu, As, Cd, Hg, Pb

Comment

Method uses General Purpose plasma conditions and He mode only. The selection of an appropriate internal standard should consider the analyte and the sample matrix.

Required Hardware

7800, x-Lens, Micro Mist Nebulizer

Summary

7800 Application Method for Elemental Impurities in Pharma, using USP<232>/ICH Q3D

Compatible Sample Types

Simple aqueous matrices and acid digested samples up to 0.4% dissolved solids

Pre-Defined Analytes

Li, V, Cr, Co, Ni, Cu, As, Se, Mo, Ru, Rh, Pd, Ag, Cd, Sn, Sb, Ba, Os, Ir, Pt, Au, Hg, Tl, Pb

Comment

Method uses General Purpose plasma conditions and He mode only, but requires the 7800. User Access Control option software is required for regulated pharma analysis. The selection of an appropriate internal standard should consider the analyte and the sample matrix.

Required Hardware

7800, x-Lens, Micro Mist Nebulizer

Summary

7800x Application Method for EPA200.8 (No minerals, without ORSs)

Compatible Sample Types

Application Method for low matrix aqueous or acidic samples (up to 0.1% Total Dissolved Solids), including drinking water, tap water, industrial water, riverine water, lake water, pond water and surface water except seawater. Also suitable for closed-vessel acid digested or extracted samples, after dilution to <0.1% Total Dissolved Solids.

Pre-Defined Analytes

Li, Be, Al, V, Cr, Mn, Co, Ni, Cu, Zn, As, Se, Mo, Ru, Rh, Pd, Cd, Ag, Sn, Sb, Ba, Ho, Hg, Tl, Pb, Th, U

Comment

Uses Low Matrix plasma conditions, and no gas mode only.

Required Hardware

7800, x-Lens, Micro Mist Nebulizer

Summary

7800 Application Method for EPA6020

Compatible Sample Types

Application Method for low or medium matrix samples (up to 0.3% Total Dissolved Solids), including diluted seawater, groundwater and mineral water, acid digested or extracted soil, sediment, sludge and industrial waste samples.

Pre-Defined Analytes

Li, Be, Na, Mg, Al, K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Rh, Ag, Cd, Sn, Sb, Ba, Ho, Hg, Tl, Pb

Comment

Method is suitable only for the 7800, due to the short pre-defined cell gas stabilization time. Uses General Purpose plasma conditions, and no gas, and He cell modes.

Required Hardware

7800, x-Lens, Micro Mist Nebulizer

Summary

7800 Application Method for Drinking Water (with ORS)

Compatible Sample Types

Application Method for low matrix aqueous or acidic samples (up to 0.1% Total Dissolved Solids), including drinking water, tap water, industrial water, except seawater. Also suitable for closed-vessel acid digested or extracted samples, after dilution to <0.1% Total Dissolved Solids.

Pre-Defined Analytes

Na, Mg, Al, K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Sr, Mo, Rh, Ag, Cd, Sn, Ba, Hg, Tl, Pb, Th, U

Comment

Method is suitable only for the 7800, due to the short pre-defined cell gas stabilization time. Uses Low Matrix plasma conditions, and no gas, and He cell modes

Required Hardware

7800, x-Lens, Micro Mist Nebulizer

Summary

8900 Application Method for Elemental Impurities in Pharma, using USP<232>/ICH Q3D

Compatible Sample Types

Simple aqueous matrices and acid digested samples up to 0.4% dissolved solids.

Pre-Defined Analytes

Li, V, Cr, Co, Ni, Cu, As, Se, Mo, Ru, Rh, Pd, Ag, Cd, Sn, Sb, Ba, Os, Ir, Pt, Au, Hg, Tl, Pb

Comment

Tune : General Purpose Cell mode : He User Access Control option software is required for regulated pharma analysis.

Required Hardware

8900 ICP-MS Triple Quad, x-Lens, Micro Mist Nebulizer

Summary

8900 Application Method for Food/Clinical

Compatible Sample Types

Application method for aqueous or closed-vessel acid digested/extracted samples of food, medicine, and cosmetics. Also suitable for filtered urine samples, and solubilized or acid digested/extracted samples of organic tissue and hair.

Pre-Defined Analytes

Be, Na, Mg, Al, K, Ca, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Mo, Ag, Cd, Sn, Sb, Ba, Pt, Hg, Tl, Pb, U

Comment

Tune : General Purpose Cell mode : No gas, He, HEHe HEHe mode is not needed if the concentration of Se is high enough.

Required Hardware

8900 ICP-MS Triple Quad, x-Lens, MicroMist Nebulizer

Summary

8900 Application Method for low matrix samples (e.g. Drinking Water)

Compatible Sample Types

Application method for low matrix aqueous or acidic samples (up to 0.1% Total Dissolved Solids), including drinking water, tap water, industrial water, riverine water, lake water, pond water, and surface water except seawater. Also suitable for closed-vessel acid digested or extracted samples, after dilution to <0.1% Total Dissolved Solids.

Pre-Defined Analytes

Be, B, Na, Mg, Al, K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Sr, Mo, Ag, Cd, Sb, Ba, Hg, Tl, Pb, Th, U

Comment

Tune : Low Matrix Cell mode : No gas, He

Required Hardware

8900 ICP-MS Triple Quad, x-Lens, MicroMist Nebulizer

Summary

8900 Application Method for Elemental Impurities in Pharmaceutical samples, using China Pharmacopoeia

Compatible Sample Types

Simple aqueous matrices and acid digested samples up to 0.4% dissolved solids.

Pre-Defined Analytes

Cu, As, Cd, Hg, Pb

Comment

Tune : General Purpose Cell mode : He

Required Hardware

8900 ICP-MS Triple Quad, x-Lens, Micro Mist Nebulizer

Summary

8900 Application Method for EPA6020

Compatible Sample Types

Application method for low or medium matrix samples (up to 0.3% Total Dissolved Solids), including diluted seawater, ground water and mineral water, acid digested or extacted soil, sediment, sludge and industiral waste samples.

Pre-Defined Analytes

Be, Na, Mg, Al, K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Ag, Cd, Sb, Ba, Hg, Tl, Pb

Comment

Tune : General Purpose Cell mode : No gas, He, O2

Required Hardware

8900 ICP-MS Triple Quad, x-Lens, MicroMist Nebulizer

Summary

8900 ICP-MS Triple Quad with s-lens application method for Ultra-Pure Water with H2 and/or NH3

Compatible Sample Types

Ultra-Pure Water

Pre-Defined Analytes

Li, Be, B, Na, Mg, Al, Si, P, S, K, Ca, Sc, Ti, V, Cr, Mn, Fe, Ni, Co, Cu, Zn, Ga, Ge, As, Se, Br, Rb, Sr, Y, Zr, Nb, Mo, Ru, Rh, Pd, Ag, Cd, In, Sn, Sb, Te, I, Cs, Ba, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Hf, W, Ta, Re, Os, Ir, Pt, Au, Hg, Tl, Pb, Bi, Th, U

Comment

Method is suitable only for the 8900 ICP-MS Triple Quad, due to the use of H2 and/or NH3 cell modes and cool plasma conditions for some analysis.

Required Hardware

8900 ICP-MS Triple Quad, s-Lens, 2.5mm injector torch, quartz spray chamber, quartz connector tube(straight), MicroFlow Nebulizer, Pt sampling cone for s-lens, Pt skimmer cone for s-lens, Brass skimmer base for s-lens.

Summary

Ultra-Pure Water analysis with m-Lens (hot only mode)

Compatible Sample Types

Ultra-Pure Water

Pre-Defined Analytes

Li, Be, B, Na, Mg, Al, Si, P, S, K, Ca, Sc, Ti, V, Cr, Mn, Fe, Ni, Co, Cu, Zn, Ga, Ge, As, Se, Br, Rb, Sr, Y, Zr, Nb, Mo, Ru, Rh, Pd, Ag, Cd, In, Sn, Sb, Te, I, Cs, Ba, La, Ce, Pr, Nd, Sm, Eu, Gd, Tb, Dy, Ho, Er, Tm, Yb, Lu, Hf, W, Ta, Re, Os, Ir, Pt, Au, Hg, Tl, Pb, Bi, Th, U

Comment

Method is applied for Ultra-Pure Water analysis with m-Lens.

Required Hardware

8900 ICP-MS Triple Quad, m-Lens, 2.5mm injector torch, Micro Flow Nebulizer with self aspiration

Summary

7850 Application Method for Elemental Impurities in Pharma, using China Pharmacopoeia.

Compatible Sample Types

Simple aqueous matrices and acid digested samples up to 0.4% dissolved solids.

Pre-Defined Analytes

Cu, As, Cd, Hg, Pb

Comment

Method uses General Purpose plasma conditions and He mode only. The selection of an appropriate internal standard should consider the analyte and the sample matrix.

Required Hardware

7850, x-Lens, Micro Mist Nebulizer

Summary

7850 Application Method for Elemental Impurities in Pharma, using USP<232>/ICH Q3D

Compatible Sample Types

Simple aqueous matrices and acid digested samples up to 0.4% dissolved solids

Pre-Defined Analytes

Li, V, Cr, Co, Ni, Cu, As, Se, Mo, Ru, Rh, Pd, Ag, Cd, Sn, Sb, Ba, Os, Ir, Pt, Au, Hg, Tl, Pb

Comment

Method uses General Purpose plasma conditions and He mode only, but requires the 7850. User Access Control option software is required for regulated pharma analysis. The selection of an appropriate internal standard should consider the analyte and the sample matrix.

Required Hardware

7850, x-Lens, Micro Mist Nebulizer

Summary

7850x Application Method for EPA200.8 (No minerals, without ORSs)

Compatible Sample Types

Application Method for low matrix aqueous or acidic samples (up to 0.1% Total Dissolved Solids), including drinking water, tap water, industrial water, riverine water, lake water, pond water and surface water except seawater. Also suitable for closed-vessel acid digested or extracted samples, after dilution to <0.1% Total Dissolved Solids.

Pre-Defined Analytes

Li, Be, Al, V, Cr, Mn, Co, Ni, Cu, Zn, As, Se, Mo, Ru, Rh, Pd, Cd, Ag, Sn, Sb, Ba, Ho, Hg, Tl, Pb, Th, U

Comment

Uses Low Matrix plasma conditions, and no gas mode only.

Required Hardware

7850, x-Lens, Micro Mist Nebulizer

Summary

7850 Application Method for EPA6020

Compatible Sample Types

Application Method for low or medium matrix samples (up to 0.3% Total Dissolved Solids), including diluted seawater, groundwater and mineral water, acid digested or extracted soil, sediment, sludge and industrial waste samples.

Pre-Defined Analytes

Li, Be, Na, Mg, Al, K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Se, Rh, Ag, Cd, Sn, Sb, Ba, Ho, Hg, Tl, Pb

Comment

Method is suitable only for the 7850, due to the short pre-defined cell gas stabilization time. Uses General Purpose plasma conditions, and no gas, and He cell modes.

Required Hardware

7850, x-Lens, Micro Mist Nebulizer

Summary

7850 Application Method for Drinking Water (with ORS)

Compatible Sample Types

Application Method for low matrix aqueous or acidic samples (up to 0.1% Total Dissolved Solids), including drinking water, tap water, industrial water, except seawater. Also suitable for closed-vessel acid digested or extracted samples, after dilution to <0.1% Total Dissolved Solids.

Pre-Defined Analytes

Na, Mg, Al, K, Ca, V, Cr, Mn, Fe, Co, Ni, Cu, Zn, As, Sr, Mo, Rh, Ag, Cd, Sn, Ba, Hg, Tl, Pb, Th, U

Comment

Method is suitable only for the 7850, due to the short pre-defined cell gas stabilization time. Uses Low Matrix plasma conditions, and no gas, and He cell modes

Required Hardware

7850, x-Lens, Micro Mist Nebulizer